Mouse CD200/OX-2 Protein (CD2-MM120)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 1.19 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Gln31-Gly232

Catalog: CD2-MM120

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Product Description Recombinant Mouse CD200/OX-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln31-Gly232.

Product Background

CD200 and its receptors are highly expressed in the lung, on epithelial cells and leukocytes, and emerging evidence links dysregulation of the CD200 pathway with asthma. Moreover, pharmacological modulation of CD200 receptors was shown to improve clinical and inflammatory outcomes of preclinical asthma models.

Product Category

Recombinant Protein

Target

CD200/OX-2
Synonyms CD200; MOX1; MOX2; My033; MRC; OX-2; OX2
Accession

Species

Mouse

Amino Acid Range

Gln31-Gly232
Molecular Weight The protein has a predicted MW of 23.6 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result.

Activity

The affinity constant of 1.19 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse CD200 R1, His Tag immobilized on CM5 Chip can bind Mouse CD200, His Tag with an affinity constant of 1.19 uM as determined in SPR assay (Biacore T200).
The purity of Mouse CD200 is greater than 95% as determined by SEC-HPLC.
Mouse CD200 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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