Mouse CD200/OX-2 Protein (CD2-MM120)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 1.19 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Exact Sequence: Gln31-Gly232

Catalog: CD2-MM120

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Product Description	Recombinant Mouse CD200/OX-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln31-Gly232.
Product Background	CD200 and its receptors are highly expressed in the lung, on epithelial cells and leukocytes, and emerging evidence links dysregulation of the CD200 pathway with asthma. Moreover, pharmacological modulation of CD200 receptors was shown to improve clinical and inflammatory outcomes of preclinical asthma models.
Product Category	Recombinant Protein

Target	CD200/OX-2
Synonyms	CD200; MOX1; MOX2; My033; MRC; OX-2; OX2
Gene/Protein ID	O54901
Species	Mouse
Exact Sequence	Gln31-Gly232
Molecular Weight	The protein has a predicted MW of 23.6 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result.
Activity	The affinity constant of 1.19 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Mouse CD200 R1, His Tag immobilized on CM5 Chip can bind Mouse CD200, His Tag with an affinity constant of 1.19 uM as determined in SPR assay (Biacore T200).
	The purity of Mouse CD200 is greater than 95% as determined by SEC-HPLC.
	Mouse CD200 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.