Mouse CD200/OX-2 Protein (CD2-MM120)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 1.19 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Gln31-Gly232
Catalog #CD2-MM120
Regular price $195.00
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Product Description

Recombinant Mouse CD200/OX-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln31-Gly232.

Product Background

CD200 and its receptors are highly expressed in the lung, on epithelial cells and leukocytes, and emerging evidence links dysregulation of the CD200 pathway with asthma. Moreover, pharmacological modulation of CD200 receptors was shown to improve clinical and inflammatory outcomes of preclinical asthma models.

Product Category

Recombinant Protein / Antibody discovery

Protein

CD200/OX-2

Synonyms

CD200; MOX1; MOX2; My033; MRC; OX-2; OX2

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Gln31-Gly232

Molecular Weight

The protein has a predicted MW of 23.6 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result.

Activity

The affinity constant of 1.19 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse CD200 R1, His Tag immobilized on CM5 Chip can bind Mouse CD200, His Tag with an affinity constant of 1.19 uM as determined in SPR assay (Biacore T200). Mouse CD200 R1, His Tag immobilized on CM5 Chip can bind Mouse CD200, His Tag with an affinity constant of 1.19 uM as determined in SPR assay (Biacore T200).
Mouse CD200 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse CD200 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse CD200 is greater than 95% as determined by SEC-HPLC. The purity of Mouse CD200 is greater than 95% as determined by SEC-HPLC.

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