Mouse CD200 R1 Protein (CD2-MM4R1)
Catalog: CD2-MM4R1
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Product Description | Recombinant Mouse CD200 R1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr26-Pro238. |
Product Background |
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid and T cell lineage. A recent report focused attention on a family of CD200Rs, but concluded that only one member used CD200 as its ligand. |
Product Category |
Recombinant Protein |
Target |
CD200 R1 |
Gene/Protein ID |
Q9ES57 |
Species |
Mouse |
Exact Sequence |
Thr26-Pro238 |
Molecular Weight | The protein has a predicted MW of 24.21 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
Activity |
The affinity constant of 1.19 uM as determined in SPR assay (Biacore T200). See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Lyophilized |
Shipping | Shipped at ambient temperature. |
Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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