Mouse CD43 Protein (CD4-MM243)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Asp20-Gly248

Catalog: CD4-MM243

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Product Description Recombinant Mouse CD43 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Asp20-Gly248.

Product Background

CD43 is a large transmembrane protein involved in T cell activation. Previous studies of CD43-/- mice in viral models have demonstrated a role for CD43 in Th1/Th2 skewing, activation of Foxp3 Treg, and T cell apoptosis. CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage. CD43 is directly involved in the contact between cells participating in a series of events such as signaling, adherence and host parasite interactions.

Product Category

Recombinant Protein

Target

CD43

Gene/Protein ID

P15702

Species

Mouse

Exact Sequence

Asp20-Gly248
Molecular Weight The protein has a predicted MW of 49.30 kDa. Due to glycosylation, the protein migrates to 75-120 kDa based on Tris-Bis PAGE result.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse CD43 is greater than 95% as determined by SEC-HPLC.
Mouse CD43 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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