Name: Mouse CD45/PTPRC Protein (PTP-MM201)
Brand: KactusBio
SKU: PTP-MM201-100UG
Price: 300.0 USD
Availability: InStock

Catalog #PTP-MM201

Size

100UG

500UG

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Product Description	Recombinant Mouse CD45/PTPRC Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln26-Lys427.
Product Background	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts.
Product Category	Recombinant Protein / Antibody discovery

Protein	CD45/PTPRC
Synonyms	L-CA; CD45; T200; PTPRC; B220; CD45R; GP180; LCA; LY5; EC 3.1.3.48
Accession	P06800-6
Species	Mouse
Biotinylated	no
Amino Acid Range	Gln26-Lys427
Molecular Weight	The protein has a predicted MW of 71.46 kDa. Due to glycosylation, the protein migrates to 100-130 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse CD45 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse CD45 is greater than 95% as determined by SEC-HPLC.