Mouse CD8 alpha/CD8A Protein (CD8-MM18A)
Mouse CD8 alpha/CD8A Protein (CD8-MM18A)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Lys28-Tyr196
Catalog #CD8-MM18A
Regular price $379.50
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Product Description

Recombinant Mouse CD8 alpha/CD8A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys28-Tyr196.

Product Background

CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.

Product Category

Recombinant Protein / Antibody discovery / CAR-T targets

Protein

CD8 alpha/CD8A

Synonyms

CD8a; Lyt-2; CD8; Leu2; MAL; p32; CD8a molecule; OKT8 T-cell antigen

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Lys28-Tyr196

Molecular Weight

The protein has a predicted MW of 20 kDa. Due to glycosylation, the protein migrates to 32-42 kDa based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse CD8 alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse CD8 alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse CD8 alpha is greater than 95% as determined by SEC-HPLC. The purity of Mouse CD8 alpha is greater than 95% as determined by SEC-HPLC.

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