Mouse CD83 Protein (CD8-MM283)
Catalog: CD8-MM283
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| Product Description | Recombinant Mouse CD83 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Met22-Ala134. |
Product Background |
CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated immune cells, although it is most highly and stably expressed by mature dendritic cells (DC). While CD83 is emerging as a promising immune modulator with therapeutic potential, some important aspects such as its ligand/s, intracellular signaling pathways and modulators of its expression are unclear. |
Product Category |
Recombinant Protein |
Target |
CD83 |
| Synonyms | CD83; HB15; BL11; CD83 molecule |
Gene/Protein ID |
O88324 |
Species |
Mouse |
Exact Sequence |
Met22-Ala134 |
| Molecular Weight | The protein has a predicted MW of 39.1 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Mouse CD83 is greater than 95% as determined by SEC-HPLC. |
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Mouse CD83 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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