SEC-HPLC chromatogram showing a single sharp protein peak at 7.0 minutes, indicating high purity and minimal aggregation.
Mouse CD96/TACTILE Protein (CD9-MM196)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Val22-Met536
Catalog #CD9-MM196
Regular price $346.50
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Product Description

Recombinant Mouse CD96/TACTILE Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val22-Met536.

Product Background

The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for immuno-oncology drug development.

Product Category

Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein

CD96/TACTILE

Synonyms

CD96 molecule; CD96; DKFZp667E2122; TACTILE

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Val22-Met536

Molecular Weight

The protein has a predicted MW of 57.9 kDa. Due to glycosylation, the protein migrates to 90-130 kDa based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse CD96 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse CD96 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse CD96 is greater than 95% as determined by SEC-HPLC. The purity of Mouse CD96 is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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