Mouse CEACAM-5/CD66e Protein (CAM-MM105)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 90% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Amino Acid Range: Gln35-Glu947
Catalog #CAM-MM105
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Size
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Mouse CEACAM-5/CD66e Protein (CAM-MM105) Summary

Product Description

 Recombinant Mouse CEACAM-5/CD66e Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln35-Glu947.

Product Background

 Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.

Product Category

 Recombinant Protein / Antibody discovery / CAR-T targets, ADC targets

Mouse CEACAM-5/CD66e Protein (CAM-MM105) Specifications/Details

Protein
 CEACAM-5/CD66e
Synonyms
 CEACAM-5; CD66e; CEA; Meconium antigen 100; Carcinoembryonic; CEACD66e; DKFZp781M2392
Accession
Species
 Mouse
Biotinylated
 no
Amino Acid Range
 Gln35-Glu947
Molecular Weight
 The protein has a predicted MW of 104.22 kDa. Due to glycosylation, the protein migrates to 120-140 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His

Fluorophore

 Unconjugated
Expression System
 HEK293
Purity
 > 90% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse CEACAM-5 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%. Mouse CEACAM-5 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.
The purity of Mouse CEACAM-5 is greater than 90% as determined by SEC-HPLC. The purity of Mouse CEACAM-5 is greater than 90% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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support@kactusbio.us

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