Mouse Complement Factor D/CFD Protein (CFD-MM201)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Ile26-Ser259

Catalog: CFD-MM201

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Product Description Recombinant Mouse Complement Factor D/CFD Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile26-Ser259.

Product Background

Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.

Product Category

Recombinant Protein

Target

Complement Factor D/CFD
Synonyms Adipsin; C3 convertase activator; Complement factor D; CFD; PFD; DF; ADN; FACTOR D; AMBP-1; EC 3.4.21; EC 3.4.21.46

Gene/Protein ID

P03953-1

Species

Mouse

Exact Sequence

Ile26-Ser259
Molecular Weight The protein has a predicted MW of 52.2 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in 20mM Tris,500mM NaCl (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Mouse Complement Factor D is greater than 95% as determined by SEC-HPLC.
Mouse Complement Factor D on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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