Mouse CXCL13/BCA-1 Protein (CXC-MM113)

  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Amino Acid Range: Ile22-Ala109

Catalog: CXC-MM113

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Product Description Recombinant Mouse CXCL13/BCA-1 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Ile22-Ala109.

Product Background

Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.

Product Category

Recombinant Protein

Target

CXCL13/BCA-1
Synonyms ANGIE; ANGIE2; BCA-1; BCA1; BLC; BLR1L; SCYB13
Accession

Species

Mouse

Amino Acid Range

Ile22-Ala109
Molecular Weight The protein has a predicted MW of 11.7 kDa. Due to glycosylation, the protein migrates to 16-20 kDa based on Tris-Bis PAGE result.

Product Tag

N-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in 50mM Tris, 500mM NaCl (pH 7.5). Normally 8% mannitol is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse CXCL13 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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