Product Description |
Recombinant Mouse CXCL13/BCA-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ile22-Ala109. |
Product Background |
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. |
Product Category |
Recombinant Protein / Antibody discovery |
Protein |
CXCL13/BCA-1 |
Synonyms |
ANGIE; ANGIE2; BCA-1; BCA1; BLC; BLR1L; SCYB13 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Ile22-Ala109 |
Molecular Weight |
The protein has a predicted MW of 37.1 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result. |
Product Tag |
N-hFc |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in 50mM Tris, 500mM NaCl (pH 7.5). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Mouse CXCL13 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse CXCL13 is greater than 95% as determined by SEC-HPLC. |
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