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Mouse CXCL13/BCA-1 Protein, Ultra Low Endotoxin (CXC-MM113-UL) Summary
Product Description |
Recombinant Mouse CXCL13/BCA-1 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Ile22-Ala109. |
Product Background |
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Mouse CXCL13/BCA-1 Protein, Ultra Low Endotoxin (CXC-MM113-UL) Specifications/Details
Protein |
CXCL13/BCA-1 |
Synonyms |
ANGIE; ANGIE2; BCA-1; BCA1; BLC; BLR1L; SCYB13 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Ile22-Ala109 |
Molecular Weight |
The protein has a predicted MW of 11.7 kDa. Due to glycosylation, the protein migrates to 16-20 kDa based on Bis-Tris PAGE result. |
Product Tag |
N-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 0.01 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in 50mM Tris, 500mM NaCl (pH 7.5). Normally 8% mannitol is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Mouse CXCL13 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
Other Available Proteins:
Finding available proteins...
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