Name: Mouse DR3/TNFRSF25 Protein (DR3-MM101)
Brand: KactusBio
SKU: DR3-MM101-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Mouse DR3, His Tag at 1ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Mouse TNFSF15, His Tag with the EC50 of 4.6ng/ml determined by ELISA (QC Test). The affinity constant of 4.56 nM as determined in SPR assay (Biacore T200).
Amino Acid Range: Gln31-Met196
Other Available Proteins:

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Catalog #DR3-MM101

Size

100UG

500UG

Order by 4pm ET for delivery on:

Mouse DR3/TNFRSF25 Protein (DR3-MM101) Summary

Product Description	Recombinant Mouse DR3/TNFRSF25 Protein is expressed from HEK293 with His tag at the C-Terminus.; It contains Gln31-Met196.
Product Background	Death Receptor 3 (DR3), also known as TNFRSF25, TRAMP, LARD, or WSL-1, is a death-domain-containing TNF-family receptor that, like its closest paralog TNFR1, binds the adaptor molecule TRADD through its cytoplasmic death domain. TRADD recruitment endows DR3 with dual-signaling capability to activate NF−κB and MAP-kinase signaling or alternatively trigger caspase activation and programmed cell death.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Mouse DR3/TNFRSF25 Protein (DR3-MM101) Specifications/Details

Protein	DR3/TNFRSF25
Synonyms	APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; TNFRSF25; LARD; TR3; TRAMP; WSL-LR
Accession	B1AWN9
Species	Mouse
Biotinylated	no
Amino Acid Range	Gln31-Met196
Molecular Weight	The protein has a predicted MW of 18.79 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Mouse DR3, His Tag at 1ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Mouse TNFSF15, His Tag with the EC50 of 4.6ng/ml determined by ELISA (QC Test). The affinity constant of 4.56 nM as determined in SPR assay (Biacore T200).
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse TNFSF15, hFc Tag captured on CM5 Chip via Protein A can bind Mouse DR3, His Tag with an affinity constant of 4.56 nM as determined in SPR assay (Biacore T200).
	Immobilized Mouse DR3, His Tag at 1ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Mouse TNFSF15, His Tag with the EC50 of 4.6ng/ml determined by ELISA (QC Test).
	Mouse DR3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Mouse TNFSF15, monomeric Fc Tag on ProA-Biosensor, can bind Mouse DR3, His Tag with an affinity constant of 22.80 nM as determined in BLI assay (Gator).
	The purity of Mouse DR3 is greater than 95% as determined by SEC-HPLC.