Product Description |
Recombinant Mouse ECSCR Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln19-Thr130. |
Product Background |
Endothelial cell-specific chemotaxis receptor (ECSCR) is a cell surface protein expressed by blood endothelial cells with roles in endothelial cell migration and signal transduction. Zebrafish ecscr is expressed in angioblasts and in axial vessels during angioblast migration and vasculogenesis. Morpholino-directed ecscr knockdown resulted in defective angioblast migration in the posterior lateral plate mesoderm, a process known to depend on vascular endothelial-derived growth factor (VEGF). |
Product Category |
Recombinant Protein |
Target |
ECSCR |
Synonyms |
ARIA; ECSCR; ECSM2 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Gln19-Thr130 |
Molecular Weight |
The protein has a predicted MW of 38.6 kDa. Due to glycosylation, the protein migrates to 48-68 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in 20mM Tris,150mM NaCl (pH 8.2). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Mouse ECSCR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse ECSCR is greater than 95% as determined by SEC-HPLC. |
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