Product Description |
Recombinant Mouse EDA2R Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Met1-Thr138. |
Product Background |
EDA2R is a member of the large family of tumor necrosis factor receptor (TNFR). Previous studies suggested that EDA2R expression might be increased in the kidneys of diabetic mice. High glucose increases EDA2R expression in kidney cells and that EDA2R induces podocyte apoptosis and dedifferentiation in high glucose milieu partially through enhanced ROS generation. |
Product Category |
Recombinant Protein |
Target |
EDA2R |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Met1-Thr138 |
Molecular Weight |
The protein has a predicted MW of 42.15 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Mouse EDA2R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse EDA2R is greater than 95% as determined by SEC-HPLC. |
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