Mouse EPHB2 Protein (EPH-MM101)
Mouse EPHB2 Protein (EPH-MM101)
Mouse EPHB2 Protein (EPH-MM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Val19-Leu543
Catalog #EPH-MM101
Regular price $264.00
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Mouse EPHB2 Protein (EPH-MM101) Summary

Product Description

Recombinant Mouse EPHB2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val19-Leu543.

Product Background

EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated pathologic characteristics of glioblastoma multiforme (GBM) such as invasion and migration. EPHB2 is epigenetically overexpressed in hypoxia, a condition highly prevalent in malignancy. Furthermore, HIF-2α is required for EPHB2 stabilization by hypoxia.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Mouse EPHB2 Protein (EPH-MM101) Specifications/Details

Protein
EPHB2
Synonyms
DRT; ERK; HEK5; TYRO5; CAPB; EK5; EPHT3; PCBC; Cek5; EphB2; EPHT3MGC87492; Nuk; Qek2; Sek3
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Val19-Leu543
Molecular Weight
The protein has a predicted MW of 59.3 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

Product Tag

C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human EPHB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human EPHB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human EPHB2 is greater than 95% as determined by SEC-HPLC. The purity of Human EPHB2 is greater than 95% as determined by SEC-HPLC.
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