Mouse EPHB2 Protein (EPH-MM101)
Mouse EPHB2 Protein (EPH-MM101)
Mouse EPHB2 Protein (EPH-MM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Val19-Leu543
Catalog #EPH-MM101
Regular price $240.00
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Product Description
Recombinant Mouse EPHB2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val19-Leu543.
Product Background
EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated pathologic characteristics of glioblastoma multiforme (GBM) such as invasion and migration. EPHB2 is epigenetically overexpressed in hypoxia, a condition highly prevalent in malignancy. Furthermore, HIF-2α is required for EPHB2 stabilization by hypoxia.
Product Category
Recombinant Protein
Target
EPHB2
Synonyms
DRT; ERK; HEK5; TYRO5; CAPB; EK5; EPHT3; PCBC; Cek5; EphB2; EPHT3MGC87492; Nuk; Qek2; Sek3
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Val19-Leu543
Molecular Weight
The protein has a predicted MW of 59.3 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human EPHB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human EPHB2 is greater than 95% as determined by SEC-HPLC.

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