Mouse Factor H/CFH Protein (CFH-MM101)
Mouse Factor H/CFH Protein (CFH-MM101)
Mouse Factor H/CFH Protein (CFH-MM101)
Mouse Factor H/CFH Protein (CFH-MM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ser875-Val1252
Catalog #CFH-MM101
/
Size

Order now, ships by:

Product Description
 Recombinant Mouse Factor H/CFH Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser875-Val1252.
Product Background
 Factor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations and polymorphisms that affect recognition of self by factor H are associated with diseases of complement dysregulation, such as age-related macular degeneration and atypical haemolytic uremic syndrome. In addition, pathogens (i.e., non-self) and cancer cells (i.e., altered-self) can hijack factor H to evade the immune response.
Product Category
 Recombinant Protein
Target
 Factor H/CFH
Synonyms
 Complement factor H; H factor 1; CFH; HF; HF1; HF2; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HUS
Accession
Species
 Mouse
Biotinylated
 no
Amino Acid Range
 Ser875-Val1252
Molecular Weight
 The protein has a predicted MW of 42.5 kDa. Due to glycosylation, the protein migrates to 60-65 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse Factor H/CFH on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse Factor H/CFH is greater than 95% as determined by SEC-HPLC.
Recently viewed