Name: Mouse Factor H/CFH Protein (CFH-MM101)
Brand: KactusBio
SKU: CFH-MM101-100UG
Price: 270.0 USD
Availability: InStock

Catalog #CFH-MM101

Size

100UG

500UG

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Product Description	Recombinant Mouse Factor H/CFH Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser875-Val1252.
Product Background	Factor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations and polymorphisms that affect recognition of self by factor H are associated with diseases of complement dysregulation, such as age-related macular degeneration and atypical haemolytic uremic syndrome. In addition, pathogens (i.e., non-self) and cancer cells (i.e., altered-self) can hijack factor H to evade the immune response.
Product Category	Recombinant Protein / Antibody discovery

Protein	Factor H/CFH
Synonyms	Complement factor H; H factor 1; CFH; HF; HF1; HF2; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HUS
Accession	NP_034018.2
Species	Mouse
Biotinylated	no
Amino Acid Range	Ser875-Val1252
Molecular Weight	The protein has a predicted MW of 42.5 kDa. Due to glycosylation, the protein migrates to 60-65 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse Factor H/CFH on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse Factor H/CFH is greater than 95% as determined by SEC-HPLC.