Mouse FAM3D Protein (FAM-MM23D)
Mouse FAM3D Protein (FAM-MM23D)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Tyr26-Met223
Catalog #FAM-MM23D
Regular price $300.00
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Product Description
Recombinant Mouse FAM3D Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Tyr26-Met223.
Product Background
The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (mouse Fam3D), is highly expressed in mouse gastrointestinal tract. Here, we demonstrate that deficiency in Fam3D is associated with impaired integrity of colonic mucosa, increased epithelial hyper-proliferation, reduced anti-microbial peptide production and increased sensitivity to chemically induced colitis associated with high incidence of cancer.
Product Category
Recombinant Protein
Target
FAM3D
Synonyms
EF7; FAM3D; OIT1
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Tyr26-Met223
Molecular Weight
The protein has a predicted MW of 48.7 kDa. Due to glycosylation, the protein migrates to 52-58 kDa based on Bis-Tris PAGE result.
Product Tag
C-hFc
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse FAM3D on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse FAM3D is greater than 95% as determined by SEC-HPLC.
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