Mouse FAM3D Protein (FAM-MM23D)
Mouse FAM3D Protein (FAM-MM23D)
  • Express System: HEK293
  • Product Tag: C-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Tyr26-Met223
Catalog #FAM-MM23D
Regular price $330.00
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Size
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Mouse FAM3D Protein (FAM-MM23D) Summary

Product Description

Recombinant Mouse FAM3D Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Tyr26-Met223.

Product Background

The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (mouse Fam3D), is highly expressed in mouse gastrointestinal tract. Here, we demonstrate that deficiency in Fam3D is associated with impaired integrity of colonic mucosa, increased epithelial hyper-proliferation, reduced anti-microbial peptide production and increased sensitivity to chemically induced colitis associated with high incidence of cancer.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Mouse FAM3D Protein (FAM-MM23D) Specifications/Details

Protein
FAM3D
Synonyms
EF7; FAM3D; OIT1
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Tyr26-Met223
Molecular Weight
The protein has a predicted MW of 48.7 kDa. Due to glycosylation, the protein migrates to 52-58 kDa based on Bis-Tris PAGE result.
Product Tag
C-hFc (IgG1)

Fluorophore

Unconjugated
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse FAM3D on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse FAM3D on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse FAM3D is greater than 95% as determined by SEC-HPLC. The purity of Mouse FAM3D is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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