Mouse FcRn Protein (FRN-MM101)
Catalog: FRN-MM101
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| Product Description | Recombinant Mouse FcRn Protein is expressed from Expi293 with His tag at the C-terminal.; It contains Ser22-Ser297 (FCGRT)&Ala21-Met119 (B2M). |
| Product Category | Recombinant Protein |
| Target | FcRn |
| Synonyms | FcRn alpha chain; FCGRT; FCRN; FCGRT&B2M |
| Gene/Protein ID | Q61559 (FCGRT)&P01887 (B2M) |
| Species | Mouse |
| Exact Sequence | Ser22-Ser297 (FCGRT)&Ala21-Met119 (B2M) |
| Molecular Weight | The protein has a predicted MW of 32.1 kDa (FCGRT)&11.7 kDa (B2M). Due to glycosylation, the protein migrates to 50-55 kDa (FCGRT)&14-15 kDa (B2M) based on Tris-Bis PAGE result. |
| Activity | The affinity constant of 4.55 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
| Product Tag | C-His |
| Express System | Expi293 |
| Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Liquid |
| Shipping | Shipped with blue ice or dry ice. |
| Formulation | Supplied as 0.22μm filtered solution in PBS (pH 7.4). Please dilute to the desired concentration according to the concentration of the solution shown on the product label. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Mouse FcRn, His Tag captured on CM5 Chip via anti-his antibody can bind Trastuzumab with an affinity constant of 4.55 nM as determined in SPR assay (Biacore T200). |
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The purity of Mouse FcRn is greater than 95% as determined by SEC-HPLC. |
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Mouse FcRn on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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