Mouse GARP&Latent TGF beta 1 Complex Protein (GAT-MM101)
Mouse GARP&Latent TGF beta 1 Complex Protein (GAT-MM101)
  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Amino Acid Range: Ala18-Leu628(GARP) & Leu30-Ser390(Latent TGF beta 1)
Catalog #GAT-MM101
Regular price $346.50
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Mouse GARP&Latent TGF beta 1 Complex Protein (GAT-MM101) Summary

Product Description

Recombinant Mouse GARP&Latent TGF beta 1 Complex Protein is expressed from HEK293 with His tag at the N-Terminus of Latent TGF beta 1.It contains Ala18-Leu628(GARP) and Leu30-Ser390(Latent TGF beta 1).

Product Background

GARP&Latent TGF Beta is a complex found on surface of many types of cells. In Tregs, GARP is involved in TCR-mediated activation of Latent TGF-β and thus promoting secretion and activation of TGF-β. Integrin αvβ8 on the surface of immune cells and other cells recognizes RGD in LAP, resulting in the release of mature TGF-β from the TGF-β&GARP complex.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Mouse GARP&Latent TGF beta 1 Complex Protein (GAT-MM101) Specifications/Details

Protein
GARP&Latent TGF beta 1 Complex
Synonyms
LRRC32; GARP; LAP; TGF-beta-1; LRRC32&TGF-beta 1; LRRC32&TGFB1; TGF-β-1; LRRC32&TGF-β 1; GARP&Latent TGF Beta; GARP&Latent TGF Beta 1
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Ala18-Leu628(GARP) & Leu30-Ser390(Latent TGF beta 1)
Molecular Weight
The protein has a predicted MW of 66.6 kDa (GARP)&41.3 kDa (Latent TGF beta 1). Due to glycosylation, the protein migrates to 70-80 kDa (GARP)&13 kDa&42-50 kDa (Latent TGF beta 1) based on Bis-Tris PAGE result.

Product Tag

N-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse GARP&Latent TGF beta 1 Complex on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse GARP&Latent TGF beta 1 Complex on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse GARP&Latent TGF beta 1 Complex is greater than 90% as determined by SEC-HPLC. The purity of Mouse GARP&Latent TGF beta 1 Complex is greater than 90% as determined by SEC-HPLC.
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