Name: Mouse GARP&Latent TGF beta 1 Complex Protein (GAT-MM101)
Brand: KactusBio
SKU: GAT-MM101-100UG
Price: 346.5 USD
Availability: InStock

Mouse GARP&Latent TGF beta 1 Complex Protein (GAT-MM101)

Mouse GARP&Latent TGF beta 1 Complex on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Mouse GARP&Latent TGF beta 1 Complex is greater than 90% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: N-His
Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Amino Acid Range: Ala18-Leu628(GARP) & Leu30-Ser390(Latent TGF beta 1)

Catalog #GAT-MM101

Size

100UG

500UG

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Product Description	Recombinant Mouse GARP&Latent TGF beta 1 Complex Protein is expressed from HEK293 with His tag at the N-Terminus of Latent TGF beta 1.It contains Ala18-Leu628(GARP) and Leu30-Ser390(Latent TGF beta 1).
Product Background	GARP&Latent TGF Beta is a complex found on surface of many types of cells. In Tregs, GARP is involved in TCR-mediated activation of Latent TGF-β and thus promoting secretion and activation of TGF-β. Integrin αvβ8 on the surface of immune cells and other cells recognizes RGD in LAP, resulting in the release of mature TGF-β from the TGF-β&GARP complex.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	GARP&Latent TGF beta 1 Complex
Synonyms	LRRC32; GARP; LAP; TGF-beta-1; LRRC32&TGF-beta 1; LRRC32&TGFB1; TGF-β-1; LRRC32&TGF-β 1; GARP&Latent TGF Beta; GARP&Latent TGF Beta 1
Accession	G3XA59(GARP)&P04202(Latent TGF beta 1)
Species	Mouse
Biotinylated	no
Amino Acid Range	Ala18-Leu628(GARP) & Leu30-Ser390(Latent TGF beta 1)
Molecular Weight	The protein has a predicted MW of 66.6 kDa (GARP)&41.3 kDa (Latent TGF beta 1). Due to glycosylation, the protein migrates to 70-80 kDa (GARP)&13 kDa&42-50 kDa (Latent TGF beta 1) based on Bis-Tris PAGE result.
Product Tag	N-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse GARP&Latent TGF beta 1 Complex on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse GARP&Latent TGF beta 1 Complex is greater than 90% as determined by SEC-HPLC.