Mouse GIP Protein (GIP-MM201)
Catalog: GIP-MM201
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| Product Description | Recombinant Mouse GIP Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu22-Gln85. |
Product Background |
The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic use of GIP was dampened by evidence that its insulinotropic activity was reduced in type 2 diabetes and by reports that it increased glucagon secretion and adipose deposition in non-diabetic individuals. |
Product Category |
Recombinant Protein |
Target |
GIP |
| Synonyms | GIP; Incretin |
Gene/Protein ID |
P48756 |
Species |
Mouse |
Exact Sequence |
Glu22-Gln85 |
| Molecular Weight | The protein has a predicted MW of 34.3 kDa. Due to glycosylation, the protein migrates to 40-45 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Mouse GIP is greater than 95% as determined by SEC-HPLC. |
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Mouse GIP on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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