Mouse GITR Ligand/TNFSF18 Protein (FSF-MM218)
Mouse GITR Ligand/TNFSF18 Protein (FSF-MM218)
  • Express System: HEK293
  • Product Tag: N-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Thr47-Ser173
Catalog #FSF-MM218
Regular price $285.00
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Product Description

Recombinant Mouse GITR Ligand/TNFSF18 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Thr47-Ser173.

Product Background

Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept.

Product Category

Recombinant Protein

Protein

GITR Ligand/TNFSF18

Synonyms

TNFSF18; AITRL; TL6; GITRL; GITR Ligand

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Thr47-Ser173

Molecular Weight

The protein has a predicted MW of 41.8 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

Product Tag

N-hFc

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse GITR Ligand on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse GITR Ligand on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse GITR Ligand is greater than 95% as determined by SEC-HPLC. The purity of Mouse GITR Ligand is greater than 95% as determined by SEC-HPLC.

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