Mouse GITR Ligand/TNFSF18 Protein (FSF-MM218)

Mouse GITR Ligand on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Mouse GITR Ligand is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: N-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Thr47-Ser173

Catalog #FSF-MM218

Size

100UG

500UG

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Product Description	Recombinant Mouse GITR Ligand/TNFSF18 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Thr47-Ser173.
Product Background	Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	GITR Ligand/TNFSF18
Synonyms	TNFSF18; AITRL; TL6; GITRL; GITR Ligand
Accession	Q7TS55
Species	Mouse
Biotinylated	no
Amino Acid Range	Thr47-Ser173
Molecular Weight	The protein has a predicted MW of 41.8 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Product Tag	N-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse GITR Ligand on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse GITR Ligand is greater than 95% as determined by SEC-HPLC.