Mouse GITR Ligand/TNFSF18 Protein (FSF-MM218)
Mouse GITR Ligand/TNFSF18 Protein (FSF-MM218)
  • Express System: HEK293
  • Product Tag: N-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Thr47-Ser173
Catalog #FSF-MM218
Regular price $313.50
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Mouse GITR Ligand/TNFSF18 Protein (FSF-MM218) Summary

Product Description

Recombinant Mouse GITR Ligand/TNFSF18 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Thr47-Ser173.

Product Background

Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept.

Product Category

Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Mouse GITR Ligand/TNFSF18 Protein (FSF-MM218) Specifications/Details

Protein
GITR Ligand/TNFSF18
Synonyms
TNFSF18; AITRL; TL6; GITRL; GITR Ligand
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Thr47-Ser173
Molecular Weight
The protein has a predicted MW of 41.8 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Product Tag
N-hFc
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse GITR Ligand on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse GITR Ligand on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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