Mouse GITR Ligand/TNFSF18 Protein (FSF-MM218)
Mouse GITR Ligand/TNFSF18 Protein (FSF-MM218)
  • Express System: HEK293
  • Product Tag: N-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Thr47-Ser173
Catalog #FSF-MM218
Regular price $313.50
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Product Description

Recombinant Mouse GITR Ligand/TNFSF18 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Thr47-Ser173.

Product Background

Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept.

Product Category

Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein

GITR Ligand/TNFSF18

Synonyms

TNFSF18; AITRL; TL6; GITRL; GITR Ligand

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Thr47-Ser173

Molecular Weight

The protein has a predicted MW of 41.8 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

Product Tag

N-hFc

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse GITR Ligand on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse GITR Ligand on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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support@kactusbio.us

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