Mouse GITR/TNFRSF18 Protein (GTR-MM101)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Exact Sequence: Ser22-His153

Catalog: GTR-MM101

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Product Description Recombinant Mouse GITR/TNFRSF18 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser22-His153.

Product Background

GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Product Category

Recombinant Protein

Target

GITR/TNFRSF18
Synonyms CD357; GITR; GITR-D; TNFRSF18; AITR

Gene/Protein ID

Q8C4K3

Species

Mouse

Exact Sequence

Ser22-His153
Molecular Weight The protein has a predicted MW of 15.2 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse GITR on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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