Name: Mouse GITR/TNFRSF18 Protein, Ultra Low Endotoxin (GTR-MM101-UL)
Brand: KactusBio
SKU: GTR-MM101-UL-100UG
Price: 327.0 USD
Availability: InStock

Mouse GITR/TNFRSF18 Protein, Ultra Low Endotoxin (GTR-MM101-UL)

Mouse GITR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Amino Acid Range: Ser22-His153

Catalog #GTR-MM101-UL

Size

100UG

500UG

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Product Description	Recombinant Mouse GITR/TNFRSF18 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser22-His153.
Product Background	GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	GITR/TNFRSF18
Synonyms	CD357; GITR; GITR-D; TNFRSF18; AITR
Accession	Q8C4K3
Species	Mouse
Biotinylated	no
Amino Acid Range	Ser22-His153
Molecular Weight	The protein has a predicted MW of 15.2 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 0.01 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.