Mouse Glypican 2/GPC2 Protein (GPC-MM121)
Mouse Glypican 2/GPC2 Protein (GPC-MM121)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: His22-Ser556
Catalog #GPC-MM121
Regular price $315.00
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Product Description
Recombinant Mouse Glypican 2/GPC2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His22-Ser556.
Product Background
Glypicans can function as coreceptors for multiple signaling molecules known for regulating cell growth, motility, and differentiation. Some members of the glypican family, including glypican 2 (GPC2) and glypican 3 (GPC3), are expressed in childhood cancers and liver cancers, respectively. Antibody-based therapies targeting glypicans are being investigated in preclinical and clinical studies, with the goal of treating solid tumors that do not respond to standard therapies.
Product Category
Recombinant Protein
Target
Glypican 2/GPC2
Synonyms
Glypican-2; 2410016G05Rik; Cerebroglycan; GPC2
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
His22-Ser556
Molecular Weight
The protein has a predicted MW of 59.9 kDa. Due to autocatalytic cleavage, the protein migrates to 32-35 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse Glypican 2/GPC2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse Glypican 2/GPC2 is greater than 95% as determined by SEC-HPLC.

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