Product Description |
Recombinant Mouse Glypican 2/GPC2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His22-Ser556. |
Product Background |
Glypicans can function as coreceptors for multiple signaling molecules known for regulating cell growth, motility, and differentiation. Some members of the glypican family, including glypican 2 (GPC2) and glypican 3 (GPC3), are expressed in childhood cancers and liver cancers, respectively. Antibody-based therapies targeting glypicans are being investigated in preclinical and clinical studies, with the goal of treating solid tumors that do not respond to standard therapies. |
Product Category |
Recombinant Protein |
Target |
Glypican 2/GPC2 |
Synonyms |
Glypican-2; 2410016G05Rik; Cerebroglycan; GPC2 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
His22-Ser556 |
Molecular Weight |
The protein has a predicted MW of 59.9 kDa. Due to autocatalytic cleavage, the protein migrates to 32-35 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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