Mouse Glypican 2/GPC2 Protein (GPC-MM121)
Mouse Glypican 2/GPC2 Protein (GPC-MM121)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: His22-Ser556
Catalog #GPC-MM121
Regular price $315.00
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Product Description

Recombinant Mouse Glypican 2/GPC2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His22-Ser556.

Product Background

Glypicans can function as coreceptors for multiple signaling molecules known for regulating cell growth, motility, and differentiation. Some members of the glypican family, including glypican 2 (GPC2) and glypican 3 (GPC3), are expressed in childhood cancers and liver cancers, respectively. Antibody-based therapies targeting glypicans are being investigated in preclinical and clinical studies, with the goal of treating solid tumors that do not respond to standard therapies.

Product Category

Recombinant Protein / Antibody discovery

Protein

Glypican 2/GPC2

Synonyms

Glypican-2; 2410016G05Rik; Cerebroglycan; GPC2

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

His22-Ser556

Molecular Weight

The protein has a predicted MW of 59.9 kDa. Due to autocatalytic cleavage, the protein migrates to 32-35 kDa based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse Glypican 2/GPC2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse Glypican 2/GPC2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse Glypican 2/GPC2 is greater than 95% as determined by SEC-HPLC. The purity of Mouse Glypican 2/GPC2 is greater than 95% as determined by SEC-HPLC.

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