Mouse GP1BB Protein (GP1-MM2BB)
Mouse GP1BB Protein (GP1-MM2BB)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Pro27-Cys147
Catalog #GP1-MM2BB
Regular price $300.00
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Product Description
Recombinant Mouse GP1BB Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Pro27-Cys147.
Product Background
The glycoprotein (GP) Ib-IX complex is the receptor on platelet surfaces that mediates their adhesion to subendothelium. It comprises three polypeptides (GP Ib alpha, GP Ib beta, GP IX), each of which belongs to a superfamily of proteins containing conserved leucine-rich motifs. Association between GP Ib alpha and GP Ib beta was demonstrated biochemically on immunoblots of detergent lysates of CHO alpha beta cells; electrophoresis under nonreducing conditions revealed the two subunits to be covalently linked through a disulfide bond.
Product Category
Recombinant Protein
Target
GP1BB
Synonyms
GP-Ib beta; GPIb-beta; GPIbB; Gp1bb; BDPLT1; BS; CD42c; GP1BB; GPIbb; GPIbbeta;GP-Ib β; GPIb-β; GPIbβ
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Pro27-Cys147
Molecular Weight
The protein has a predicted MW of 39.5 kDa. Due to glycosylation, the protein migrates to 46-50 kDa based on Bis-Tris PAGE result.
Product Tag
C-hFc
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse GP1BB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse GP1BB is greater than 95% as determined by SEC-HPLC.

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