Product Description |
Recombinant Mouse GP1BB Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Pro27-Cys147. |
Product Background |
The glycoprotein (GP) Ib-IX complex is the receptor on platelet surfaces that mediates their adhesion to subendothelium. It comprises three polypeptides (GP Ib alpha, GP Ib beta, GP IX), each of which belongs to a superfamily of proteins containing conserved leucine-rich motifs. Association between GP Ib alpha and GP Ib beta was demonstrated biochemically on immunoblots of detergent lysates of CHO alpha beta cells; electrophoresis under nonreducing conditions revealed the two subunits to be covalently linked through a disulfide bond. |
Product Category |
Recombinant Protein |
Protein |
GP1BB |
Synonyms |
GP-Ib beta; GPIb-beta; GPIbB; Gp1bb; BDPLT1; BS; CD42c; GP1BB; GPIbb; GPIbbeta;GP-Ib β; GPIb-β; GPIbβ |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Pro27-Cys147 |
Molecular Weight |
The protein has a predicted MW of 39.5 kDa. Due to glycosylation, the protein migrates to 46-50 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Mouse GP1BB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse GP1BB is greater than 95% as determined by SEC-HPLC. |
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