Product Description |
Recombinant Mouse ICOS/CD278(C137S, C138S) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu21-Leu144(C137S, C138S). |
Product Background |
Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. |
Product Category |
Recombinant Protein |
Target |
ICOS/CD278 (C137S, C138S) |
Synonyms |
AILIM; CD278; CRP-1; CVID1; ICOS; MGC39850 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Glu21-Leu144(C137S, C138S) |
Molecular Weight |
The protein has a predicted MW of 15.3 kDa. Due to glycosylation, the protein migrates to 27-38 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Mouse ICOS (C137S, C138S) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse ICOS (C137S, C138S) is greater than 95% as determined by SEC-HPLC. |
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