Mouse ICOS/CD278 (C137S, C138S) Protein (ICO-MM102)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Glu21-Leu144(C137S, C138S)

Catalog: ICO-MM102

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Product Description Recombinant Mouse ICOS/CD278(C137S, C138S) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu21-Leu144(C137S, C138S).

Product Background

Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1.

Product Category

Recombinant Protein

Target

ICOS/CD278 (C137S, C138S)
Synonyms AILIM; CD278; CRP-1; CVID1; ICOS; MGC39850

Gene/Protein ID

Q9WVS0

Species

Mouse

Exact Sequence

Glu21-Leu144(C137S, C138S)
Molecular Weight The protein has a predicted MW of 15.3 kDa. Due to glycosylation, the protein migrates to 27-38 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse ICOS (C137S, C138S) is greater than 95% as determined by SEC-HPLC.
Mouse ICOS (C137S, C138S) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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