Mouse IgE Protein (IGE-MM401)
Mouse IgE Protein (IGE-MM401)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Asp198-Ser421
Catalog #IGE-MM401
Regular price $375.00
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Product Description

Recombinant Mouse IgE Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp198-Ser421.

Product Background

Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcεRI and CD23 (FcεRII). IgE and its interactions with these receptors are therefore potential targets for therapeutic intervention, and exciting progress has been made in this direction. Furthermore, recent structural studies of IgE-Fc, the two receptors, and of their complexes, have revealed a remarkable degree of plasticity at the IgE-CD23 interface and an even more remarkable degree of dynamic flexibility within the IgE molecule.

Product Category

Recombinant Protein / Antibody discovery

Protein

IgE

Synonyms

Ig epsilon chain C region;IgE

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Asp198-Ser421

Molecular Weight

The protein has a predicted MW of 28.2 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result.

Product Tag

C-His-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse IgE on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse IgE on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse IgE is greater than 95% as determined by SEC-HPLC. The purity of Mouse IgE is greater than 95% as determined by SEC-HPLC.

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