Mouse IGFBP-3R Protein (IGF-MM23R)
Mouse IGFBP-3R Protein (IGF-MM23R)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gly39-Arg204
Catalog #IGF-MM23R
Regular price $300.00
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Product Description

Recombinant Mouse IGFBP-3R Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly39-Arg204.

Product Background

Insulin-like growth factor-binding protein-3 (IGFBP-3) is a multifunctional protein known for modulating mitogenic and metabolic actions of IGFs as well as exerting a variety of biological actions not involving IGF. IGFBP-3 inhibits airway inflammation and hyper-responsiveness via an IGF-independent mechanism that involves activation of IGFBP-3R signaling and cross-talk with NF-κB signaling. The IGFBP-3/IGFBP-3R system therefore plays a pivotal role in the pathogenesis of asthma and can serve as a newly identified potential therapeutic target for this debilitating disease.

Product Category

Recombinant Protein / Antibody discovery

Protein

IGFBP-3R

Synonyms

IGFBP-3R; GFBP3R; LOC124446; TMEM219

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Gly39-Arg204

Molecular Weight

The protein has a predicted MW of 44.4 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

Product Tag

C-hFc

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse IGFBP-3R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse IGFBP-3R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse IGFBP-3R is greater than 95% as determined by SEC-HPLC. The purity of Mouse IGFBP-3R is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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