Name: Mouse IGFBP-3R Protein (IGF-MM23R)
Brand: KactusBio
SKU: IGF-MM23R-100UG
Price: 300.0 USD
Availability: InStock

Catalog #IGF-MM23R

Size

100UG

500UG

Order now, ships by:

Product Description	Recombinant Mouse IGFBP-3R Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly39-Arg204.
Product Background	Insulin-like growth factor-binding protein-3 (IGFBP-3) is a multifunctional protein known for modulating mitogenic and metabolic actions of IGFs as well as exerting a variety of biological actions not involving IGF. IGFBP-3 inhibits airway inflammation and hyper-responsiveness via an IGF-independent mechanism that involves activation of IGFBP-3R signaling and cross-talk with NF-κB signaling. The IGFBP-3/IGFBP-3R system therefore plays a pivotal role in the pathogenesis of asthma and can serve as a newly identified potential therapeutic target for this debilitating disease.
Product Category	Recombinant Protein / Antibody discovery

Protein	IGFBP-3R
Synonyms	IGFBP-3R; GFBP3R; LOC124446; TMEM219
Accession	Q9D123-1
Species	Mouse
Biotinylated	no
Amino Acid Range	Gly39-Arg204
Molecular Weight	The protein has a predicted MW of 44.4 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse IGFBP-3R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse IGFBP-3R is greater than 95% as determined by SEC-HPLC.