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Mouse IGFBP-7 Protein, Ultra Low Endotoxin (IGF-MM2BP-UL) Summary
Product Description |
Recombinant Mouse IGFBP-7 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Ser26-Leu281. |
Product Background |
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Mouse IGFBP-7 Protein, Ultra Low Endotoxin (IGF-MM2BP-UL) Specifications/Details
Protein |
IGFBP-7 |
Synonyms |
IGFBP-7; IBP7; AGM; FSTL2; IGFBP-7v; IGFBPRP1; MAC25; PSF; RAMSVPS; TAF |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Ser26-Leu281 |
Molecular Weight |
The protein has a predicted MW of 53.03 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result. |
Activity |
The affinity constant of 1.67 uM as determined in SPR assay (Biacore T200). |
Product Tag |
C-hFc (IgG1) |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.01 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
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Mouse IGFBP-7, hFc Tag captured on CM5 Chip via Protein A can bind Human CD93, His Tag with an affinity constant of 1.67 uM as determined in SPR assay (Biacore T200) (QC Test). |
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Mouse IGFBP-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Mouse IGFBP-7 is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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