Mouse IGFBP2 Protein (IGF-MM102)
Catalog: IGF-MM102
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| Product Description | Recombinant Mouse IGFBP2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu35-Gln305. |
Product Background |
Insulin-like growth factor (IGF) binding protein 2 (IGFBP2) was discovered and identified as an IGF system regulator, controlling the distribution, function, and activity of IGFs in the pericellular space. IGFBP2 is a developmentally regulated gene that is highly expressed in embryonic and fetal tissues and markedly decreases after birth.IGFBP2 is upregulated and promotes several key oncogenic processes, such as epithelial-to-mesenchymal transition, cellular migration, invasion, angiogenesis, stemness, transcriptional activation, and epigenetic programming via signaling that is often independent of IGFs. |
Product Category |
Recombinant Protein |
Target |
IGFBP2 |
| Synonyms | IBP-2; IGFBP-2; BP2; AI255832; mIGFBP-2; IGFBP2; IGF-BP53 |
Gene/Protein ID |
P47877 |
Species |
Mouse |
Exact Sequence |
Glu35-Gln305 |
| Molecular Weight | The protein has a predicted MW of 30.6 kDa. Due to glycosylation, the protein migrates to 32-40 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Mouse IGFBP2 is greater than 95% as determined by SEC-HPLC. |
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Mouse IGFBP2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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