Mouse IGFBP2 Protein (IGF-MM102)
Mouse IGFBP2 Protein (IGF-MM102)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Glu35-Gln305
Catalog #IGF-MM102
Regular price $270.00
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Product Description
Recombinant Mouse IGFBP2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu35-Gln305.
Product Background
Insulin-like growth factor (IGF) binding protein 2 (IGFBP2) was discovered and identified as an IGF system regulator, controlling the distribution, function, and activity of IGFs in the pericellular space. IGFBP2 is a developmentally regulated gene that is highly expressed in embryonic and fetal tissues and markedly decreases after birth.IGFBP2 is upregulated and promotes several key oncogenic processes, such as epithelial-to-mesenchymal transition, cellular migration, invasion, angiogenesis, stemness, transcriptional activation, and epigenetic programming via signaling that is often independent of IGFs.
Product Category
Recombinant Protein
Target
IGFBP2
Synonyms
IBP-2; IGFBP-2; BP2; AI255832; mIGFBP-2; IGFBP2; IGF-BP53
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Glu35-Gln305
Molecular Weight
The protein has a predicted MW of 30.6 kDa. Due to glycosylation, the protein migrates to 32-40 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse IGFBP2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse IGFBP2 is greater than 95% as determined by SEC-HPLC.

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