Mouse IL-1 alpha/IL-1A Protein (IL1-MM10A)
|Recombinant Mouse IL-1 alpha/IL-1A Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ser115-Ser270.
|The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases.
|The protein has a predicted MW of 19.08 kDa. Due to glycosylation, the protein migrates to 24-30 kDa based on Tris-Bis PAGE result.
|The affinity constant of 51.22 nM as determined in SPR assay (Biacore T200). See testing image for detail.
|> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
|Less than 1EU per ug by the LAL method.
|Shipped with dry ice.
|Supplied as 0.22 um filtered solution in PBS (pH 7.4).
|Stability And Storage
|Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.