Mouse IL-11R alpha Protein (ILR-MM111)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Ser24-Ala372

Catalog: ILR-MM111

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Product Description Recombinant Mouse IL-11R alpha Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser24-Ala372.

Product Background

Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human cancer cells expressed a functional IL-11Ra subunit, which triggered signal transduction either by exogenous recombinant human IL-11 or by autocrine production of IL-11 in cells cultured under hypoxic conditions.

Product Category

Recombinant Protein

Target

IL-11R alpha

Gene/Protein ID

Q64385

Species

Mouse

Exact Sequence

Ser24-Ala372
Molecular Weight The protein has a predicted MW of 39.19 kDa. Due to glycosylation, the protein migrates to 48-58 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse IL-11R alpha is greater than 95% as determined by SEC-HPLC.
Mouse IL-11R alpha on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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