Name: Mouse IL-12 Protein (IL1-MM112)
Brand: KactusBio
SKU: IL1-MM112-100UG
Price: 495.0 USD
Availability: InStock

Catalog #IL1-MM112

Size

100UG

500UG

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Mouse IL-12 Protein (IL1-MM112) Summary

Product Description	Recombinant Mouse IL-12 Protein is expressed from HEK293 with His tag at the C-Terminus of IL-12A.It contains Arg23-Ala215(IL-12A) and Met23-Ser335(IL-12B).
Product Background	Interleukin 12 (IL-12) is a pleiotropic cytokine that plays an essential role in Th1-type immune response against cancer, a condition where cells in a particular part of the body grow and reproduce uncontrollably.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Mouse IL-12 Protein (IL1-MM112) Specifications/Details

Protein	IL-12
Synonyms	CLMF; CLMF2; IL-12A; IL-12B; IL12; IL12 p70; IMD28; IMD29; NFSK; NKSF1; NKSF2; P35; IL-12 subunit p35; IL12A; interleukin 12
Accession	P43431(IL-12A)&P43432(IL-12B)
Species	Mouse
Biotinylated	no
Amino Acid Range	Arg23-Ala215(IL-12A) & Met23-Ser335(IL-12B)
Molecular Weight	The protein has a predicted MW of 22.80 kDa(IL-12A)&35.79 kDa(IL-12B). Due to glycosylation, the protein migrates to 25-30 kDa(IL-12A)&45-55 kDa(IL-12B) based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse IL-12 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is 0.5 - 2 ng/mL.
	The purity of Mouse IL-12 is greater than 95% as determined by SEC-HPLC.