Mouse IL-12 Protein (IL1-MM112)
Catalog: IL1-MM112
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| Product Description | Recombinant Mouse IL-12 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg23-Ala215(IL-12A)&Met23-Ser335(IL-12B). |
Product Background |
Interleukin 12 (IL-12) is a pleiotropic cytokine that plays an essential role in Th1-type immune response against cancer, a condition where cells in a particular part of the body grow and reproduce uncontrollably. |
Product Category |
Recombinant Protein |
Target |
IL-12 |
| Accession | |
Species |
Mouse |
Amino Acid Range |
Arg23-Ala215(IL-12A) & Met23-Ser335(IL-12B) |
| Molecular Weight | The protein has a predicted MW of 22.80 kDa(IL-12A)&35.79 kDa(IL-12B). Due to glycosylation, the protein migrates to 25-30 kDa(IL-12A)&45-55 kDa(IL-12B) based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is 0.5 - 2 ng/mL. |
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The purity of Mouse IL-12 is greater than 95% as determined by SEC-HPLC. |
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Mouse IL-12 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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