Mouse IL-17A/CTLA-8 Protein (ILA-MM117)
  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Mouse IL-17A, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-17R alpha, hFc Tag (Cat. CD7-MM2RA) with the EC50 of 5.1ng/ml determined by ELISA.
  • Amino Acid Range: Ala26-Ala158
Catalog #ILA-MM117
Regular price $347.00
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Mouse IL-17A/CTLA-8 Protein (ILA-MM117) Summary

Product Description

Recombinant Mouse IL-17A/CTLA-8 Protein is expressed from HEK293 with His tag at the N-terminus.It contains Ala26-Ala158.

Product Background

Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery/Others

Mouse IL-17A/CTLA-8 Protein (ILA-MM117) Specifications/Details

Protein
IL-17A/CTLA-8
Synonyms
CTLA-8; IL17; IL17A; IL-17CTLA-8; interleukin 17A
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Ala26-Ala158
Molecular Weight
The protein has a predicted MW of 16.07 kDa. Due to glycosylation, the protein migrates to 18-24 kDa and 25-28 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Mouse IL-17A, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-17R alpha, hFc Tag (Cat. CD7-MM2RA) with the EC50 of 5.1ng/ml determined by ELISA.
Product Tag
N-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Mouse IL-17A, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-17R alpha, hFc Tag (Cat. CD7-MM2RA) with the EC50 of 5.1ng/ml determined by ELISA. Immobilized Mouse IL-17A, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-17R alpha, hFc Tag (Cat. CD7-MM2RA) with the EC50 of 5.1ng/ml determined by ELISA.
Mouse IL-17A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse IL-17A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse IL-17A is greater than 95% as determined by SEC-HPLC. The purity of Mouse IL-17A is greater than 95% as determined by SEC-HPLC.
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