Mouse IL-17A/CTLA-8 Protein (ILA-MM417)

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Tris-Bis PAGE
Activity: Immobilized Mouse IL-17A, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-17RA, hFc Tag with the EC50 of 122.6ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Ala26-Ala158

Catalog: ILA-MM417

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Product Description	Recombinant Mouse IL-17A/CTLA-8 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala26-Ala158.
Product Background	Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.
Product Category	Recombinant Protein

Target	IL-17A/CTLA-8
Synonyms	CTLA-8; IL17; IL17A; IL-17CTLA-8; interleukin 17A
Gene/Protein ID	Q62386-1
Species	Mouse
Exact Sequence	Ala26-Ala158
Molecular Weight	The protein has a predicted MW of 18 kDa. Due to glycosylation, the protein migrates to 20-28 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Mouse IL-17A, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-17RA, hFc Tag with the EC50 of 122.6ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His-Avi
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Mouse IL-17A, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-17RA, hFc Tag with the EC50 of 122.6ng/ml determined by ELISA.
	Mouse IL-17A on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.