Mouse IL-17R alpha/CD217 Protein (CD7-MM2RA)
Mouse IL-17R alpha/CD217 Protein (CD7-MM2RA)
Mouse IL-17R alpha/CD217 Protein (CD7-MM2RA)
Mouse IL-17R alpha/CD217 Protein (CD7-MM2RA)
Mouse IL-17R alpha/CD217 Protein (CD7-MM2RA)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Mouse IL-17A, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-17R alpha, hFc Tag with the EC50 of 29.6ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Ser32-Trp322
Catalog #CD7-MM2RA
Regular price $225.00
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Product Description

Recombinant Mouse IL-17R alpha/CD217 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser32-Trp322.

Product Background

Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restricted to activated T cells, the IL‑17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL‑17 R gene was localized to chromosome 22.

Product Category

Recombinant Protein / Antibody discovery

Protein

IL-17R alpha/CD217

Synonyms

CD217; CDw217; IL-17RA; IL17R; CANDF5; IL-17R; IL-17R-alpha; IL17Rα

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Ser32-Trp322

Molecular Weight

The protein has a predicted MW of 60.1 kDa. Due to glycosylation, the protein migrates to 95-110 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Mouse IL-17A, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-17R alpha, hFc Tag with the EC50 of 29.6ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-hFc

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Mouse IL-17A, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-17R alpha, hFc Tag with the EC50 of 29.6ng/ml determined by ELISA (QC Test). Immobilized Mouse IL-17A, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-17R alpha, hFc Tag with the EC50 of 29.6ng/ml determined by ELISA (QC Test).
Immobilized Mouse IL-17F, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Mouse IL-17R alpha, hFc Tag with the EC50 of 0.2ug/ml determined by ELISA. Immobilized Mouse IL-17F, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Mouse IL-17R alpha, hFc Tag with the EC50 of 0.2ug/ml determined by ELISA.
Mouse IL-17R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse IL-17R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse IL-17R alpha is greater than 95% as determined by SEC-HPLC. The purity of Mouse IL-17R alpha is greater than 95% as determined by SEC-HPLC.

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