Mouse IL-17RB Protein, Ultra Low Endotoxin (IL1-MM1RB-UL)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Arg18-Gly286
Catalog #IL1-MM1RB-UL
Regular price $327.00
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Mouse IL-17RB Protein, Ultra Low Endotoxin (IL1-MM1RB-UL) Summary

Product Description

Recombinant Mouse IL-17RB Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg18-Gly286.

Product Background

Among inflammatory mediators, a growing body of evidence emphasizes the contribution of the interleukin 17 (IL-17) cytokine family in malignant diseases. Besides IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. In mouse models, IL-17B signaling through IL-17RB directly promotes cancer cell survival, proliferation, and migration, and induces resistance to conventional chemotherapeutic agents.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Mouse IL-17RB Protein, Ultra Low Endotoxin (IL1-MM1RB-UL) Specifications/Details

Protein
IL-17RB
Synonyms
IL-17 receptor B; IL-17RB; IL-17ER; Evi27; IL-17 RH1; IL-17ER; IL17RB
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Arg18-Gly286
Molecular Weight
The protein has a predicted MW of 30.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 0.01 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse IL-17RB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse IL-17RB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse IL-17RB is greater than 95% as determined by SEC-HPLC. The purity of Mouse IL-17RB is greater than 95% as determined by SEC-HPLC.
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