Mouse IL-17RB Protein, Ultra Low Endotoxin (IL1-MM1RB-UL)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Arg18-Gly286
Catalog #IL1-MM1RB-UL
Regular price $327.00
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Product Description

Recombinant Mouse IL-17RB Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg18-Gly286.

Product Background

Among inflammatory mediators, a growing body of evidence emphasizes the contribution of the interleukin 17 (IL-17) cytokine family in malignant diseases. Besides IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. In mouse models, IL-17B signaling through IL-17RB directly promotes cancer cell survival, proliferation, and migration, and induces resistance to conventional chemotherapeutic agents.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Protein

IL-17RB

Synonyms

IL-17 receptor B; IL-17RB; IL-17ER; Evi27; IL-17 RH1; IL-17ER; IL17RB

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Arg18-Gly286

Molecular Weight

The protein has a predicted MW of 30.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 0.01 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse IL-17RB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse IL-17RB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse IL-17RB is greater than 95% as determined by SEC-HPLC. The purity of Mouse IL-17RB is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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