Mouse IL-18BP Protein (IL8-MM2BP)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Thr29-Ala193

Catalog: IL8-MM2BP


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Product Description Recombinant Mouse IL-18BP Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Thr29-Ala193.

Product Background

Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice.

Product Category

Recombinant Protein


Synonyms IL-18BP; Igifbp

Gene/Protein ID




Exact Sequence

Molecular Weight The protein has a predicted MW of 44.7 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Tris-Bis PAGE result.

Product Tag


Express System

Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse IL-18BP is greater than 95% as determined by SEC-HPLC.
Mouse IL-18BP on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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