Mouse IL-1R3/IL-1 RAcP Protein (IL1-MM1R3)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Ser21-Thr367

Catalog: IL1-MM1R3

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Product Description Recombinant Mouse IL-1R3/IL-1 RAcP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser21-Thr367.

Product Background

Interleukin (IL)-1R3 is the co-receptor in three signaling pathways that involve six cytokines of the IL-1 family (IL-1α, IL-1β, IL-33, IL-36α, IL-36β and IL-36γ). In many diseases, multiple cytokines contribute to disease pathogenesis. For example, in asthma, both IL-33 and IL-1 are of major importance, as are IL-36 and IL-1 in psoriasis.

Product Category

Recombinant Protein

Target

IL-1R3/IL-1 RAcP
Synonyms IL1RAP; C3orf13; IL-1 R3; IL-1 RAcP

Gene/Protein ID

Q61730-1

Species

Mouse

Exact Sequence

Ser21-Thr367
Molecular Weight The protein has a predicted MW of 41.1 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse IL-1R3 is greater than 95% as determined by SEC-HPLC.
Mouse IL-1R3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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