• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 2.39 uM as determined in SPR assay (Biacore T200).
  • Amino Acid Range: Ala27-Glu240
Catalog #CD1-MM122
Price
Regular price $000
Regular price Sale price $000
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Size
Avantor VWR Fisher Scientific

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Mouse IL-2 R beta/CD122 Protein (CD1-MM122) Summary

Product Description

 Recombinant Mouse IL-2 R beta/CD122 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala27-Glu240.

Product Background

 IL-2 R beta is a member of the cytokine receptor superfamily. Human IL-2 R beta cDNA encodes a 551 amino acid residue precursor Type I membrane protein with a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. Functional IL-2 receptors can exist in two affinity states on cell surfaces, the high affinity complex consisting of heterotrimers of the alpha, beta, and gamma chains, and the intermediate affinity complex comprising heterodimers of the beta and gamma chains.

Mouse IL-2 R beta/CD122 Protein (CD1-MM122) Specifications/Details

Protein
 IL-2 R beta/CD122
Synonyms
 CD122; IL-15 R beta; IL-2 R beta; IL-2R subunit beta; IL2RB; P70-75; p75; RP5-1170K4.6; IL-15 R β; IL-2 R β; IL-2R subunit β;IL15R beta; IL2R beta; IL2R subunit beta; IL15R β; IL2R β; IL2R subunit β;IL-15 R b; IL15R b; IL-2 R b; IL2R b; IL-2R subunit b; IL2R subunit b
Accession
Species
 Mouse
Biotinylated
 no
Amino Acid Range
 Ala27-Glu240
Molecular Weight
 The protein has a predicted MW of 26.13 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Activity
 The affinity constant of 2.39 uM as determined in SPR assay (Biacore T200).
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse IL-2 R beta, His Tag captured on CM5 Chip via Anti-His Antibody can bind Human IL-2, No Tag (Cat. IL2-HM001) with an affinity constant of 2.39 uM as determined in SPR assay (Biacore T200). Mouse IL-2 R beta, His Tag captured on CM5 Chip via Anti-His Antibody can bind Human IL-2, No Tag (Cat. IL2-HM001) with an affinity constant of 2.39 uM as determined in SPR assay (Biacore T200).
Mouse IL-2 R beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse IL-2 R beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse IL-2 R beta is greater than 95% as determined by SEC-HPLC. The purity of Mouse IL-2 R beta is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
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