Name: Mouse IL-21R Protein (ILR-MM121)
Brand: KactusBio
SKU: ILR-MM121-100UG
Price: 315.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Mouse IL-21R, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Mouse IL-21, His Avi Tag with the EC50 of 4.1ng/ml determined by ELISA.
Amino Acid Range: Cys20-His237

Catalog #ILR-MM121

Size

100UG

500UG

Order by 4pm ET for delivery on:

Mouse IL-21R Protein (ILR-MM121) Summary

Product Description	Recombinant Mouse IL-21R Protein is expressed from HEK293 with His tag at the C-terminus.It contains Cys20-His237.
Product Background	IL-21 and IL-21R were highly expressed in the lesional skin and peripheral blood of psoriasis patients. IL-21 promoted CD4 T cells proliferation and Th17 cells differentiation and inhibiting Treg cells differentiation by upregulating RORγt expression and downregulating Foxp3 expression, with increased expression and secretion of IL-17A and IL-22.Microbial translocation and the associated immune activation during HIV-1 infection may lead to high expression levels of the IL-21R activation marker in RM B cells, a feature associated with increased apoptosis and a reduced number of these cells in the circulation.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery/Others

Mouse IL-21R Protein (ILR-MM121) Specifications/Details

Protein	IL-21R
Synonyms	IL-21 receptor; IL21R; CD360; NILR
Accession	Q9JHX3
Species	Mouse
Biotinylated	no
Amino Acid Range	Cys20-His237
Molecular Weight	The protein has a predicted MW of 26.64 kDa. Due to glycosylation, the protein migrates to 38-52 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Mouse IL-21R, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Mouse IL-21, His Avi Tag with the EC50 of 4.1ng/ml determined by ELISA.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Mouse IL-21R, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Mouse IL-21, His Avi Tag with the EC50 of 4.1ng/ml determined by ELISA.
	Mouse IL-21R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse IL-21R is greater than 95% as determined by SEC-HPLC.

Other Available Proteins:

Finding available proteins...

Loading...