Name: Mouse IL-23 alpha&IL-12 beta Protein (IL2-MM1AB)
Brand: KactusBio
SKU: IL2-MM1AB-100UG
Price: 520.3 USD
Availability: InStock

Mouse IL-23 alpha&IL-12 beta Protein (IL2-MM1AB)

Mouse IL-23R, His Tag immobilized on CM5 Chip can bind Mouse IL-23 alpha&IL-12 beta, His Tag with an affinity constant of 6.31 nM as determined in SPR assay (Biacore T200).

Mouse IL-23 alpha&IL-12 beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Mouse IL-23 alpha&IL-12 beta is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: N-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 6.31 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Val22-Ala196(IL-23 alpha) & Met23-Ser335(IL-12 beta)

Catalog #IL2-MM1AB

Size

100UG

500UG

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Product Description	Recombinant Mouse IL-23 alpha&IL-12 beta Protein is expressed from HEK293 with His tag at the N-Terminus of IL-23 alpha.It contains Val22-Ala196(IL-23 alpha)and Met23-Ser335(IL-12 beta).
Product Background	Interleukin (IL)-12 and IL-23 belong to the IL-12 type family and are composite cytokines, consisting of the common β subunit p40 and the specific cytokine α subunit p35 and p19, respectively. IL-12 signals via the IL-12Rβ1·IL-12Rβ2 receptor complex, and IL-23 uses also IL-12Rβ1 but engages IL-23R as second receptor.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	IL-23 alpha&IL-12 beta
Synonyms	IL23 alpha; IL12 beta; IL23 alpha&IL12 beta ; IL12 β; IL23 alpha&IL12 β
Accession	Q9EQ14-1(IL-23 alpha)&P43432-1(IL-12 beta)
Species	Mouse
Biotinylated	no
Amino Acid Range	Val22-Ala196(IL-23 alpha) & Met23-Ser335(IL-12 beta)
Molecular Weight	The protein has a predicted MW of 20.8 (Mouse IL-23 alpha)&35.8 (Mouse IL-12 beta) kDa. Due to glycosylation, the protein migrates to 22 (Mouse IL-23 alpha)&45-50 (Mouse IL-12 beta) kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 6.31 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	N-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse IL-23R, His Tag immobilized on CM5 Chip can bind Mouse IL-23 alpha&IL-12 beta, His Tag with an affinity constant of 6.31 nM as determined in SPR assay (Biacore T200).
	Mouse IL-23 alpha&IL-12 beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse IL-23 alpha&IL-12 beta is greater than 95% as determined by SEC-HPLC.