Name: Mouse IL-23 alpha&IL-12 beta Protein (IL2-MM1AB)
Brand: KactusBio
SKU: IL2-MM1AB-100UG
Price: 520.3 USD
Availability: InStock

Mouse IL-23 alpha&IL-12 beta Protein (IL2-MM1AB)

Mouse IL-23R, His Tag immobilized on CM5 Chip can bind Mouse IL-23 alpha&IL-12 beta, His Tag with an affinity constant of 6.31 nM as determined in SPR assay (Biacore T200).

Mouse IL-23 alpha&IL-12 beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Mouse IL-23 alpha&IL-12 beta is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: N-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 6.31 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Val22-Ala196(IL-23 alpha) & Met23-Ser335(IL-12 beta)

Catalog #IL2-MM1AB

Size

100UG

500UG

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Product Description	Recombinant Mouse IL-23 alpha&IL-12 beta Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Val22-Ala196(IL-23 alpha)&Met23-Ser335(IL-12 beta).
Product Background	Interleukin (IL)-12 and IL-23 belong to the IL-12 type family and are composite cytokines, consisting of the common β subunit p40 and the specific cytokine α subunit p35 and p19, respectively. IL-12 signals via the IL-12Rβ1·IL-12Rβ2 receptor complex, and IL-23 uses also IL-12Rβ1 but engages IL-23R as second receptor.
Product Category	Recombinant Protein / Antibody discovery

Protein	IL-23 alpha&IL-12 beta
Synonyms	IL23 alpha; IL12 beta; IL23 alpha&IL12 beta ; IL12 β; IL23 alpha&IL12 β
Accession	Q9EQ14-1(IL-23 alpha)&P43432-1(IL-12 beta)
Species	Mouse
Biotinylated	no
Amino Acid Range	Val22-Ala196(IL-23 alpha) & Met23-Ser335(IL-12 beta)
Molecular Weight	The protein has a predicted MW of 20.8 (Mouse IL-23 alpha)&35.8 (Mouse IL-12 beta) kDa. Due to glycosylation, the protein migrates to 22 (Mouse IL-23 alpha)&45-50 (Mouse IL-12 beta) kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 6.31 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	N-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse IL-23R, His Tag immobilized on CM5 Chip can bind Mouse IL-23 alpha&IL-12 beta, His Tag with an affinity constant of 6.31 nM as determined in SPR assay (Biacore T200).
	Mouse IL-23 alpha&IL-12 beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse IL-23 alpha&IL-12 beta is greater than 95% as determined by SEC-HPLC.