Mouse IL-5 R alpha/CD125 Protein (ILR-MM15R)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 0.495 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Asp18-His339
Catalog #ILR-MM15R
Regular price $231.00
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Product Description

Recombinant Mouse IL-5 R alpha/CD125 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp18-His339.

Product Background

Interleukin‑5 Receptor alpha (IL‑5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5.

Product Category

Recombinant Protein / Antibody discovery

Protein

IL-5 R alpha

Synonyms

CD125; CDw125CD125; HSIL5R3; IL-5 R alpha; IL-5R subunit alpha; IL5R; IL5RA; IL-5Ra; MGC26560

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Asp18-His339

Molecular Weight

The protein has a predicted MW of 37.7 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

Activity

The affinity constant of 0.495 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCl (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse IL-5 R alpha, His Tag immobilized on CM5 Chip can bind Mouse IL-5, His Tag with an affinity constant of 0.495 uM as determined in SPR assay (Biacore T200). Mouse IL-5 R alpha, His Tag immobilized on CM5 Chip can bind Mouse IL-5, His Tag with an affinity constant of 0.495 uM as determined in SPR assay (Biacore T200).
Mouse IL-5 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse IL-5 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse IL-5 R alpha is greater than 95% as determined by SEC-HPLC. The purity of Mouse IL-5 R alpha is greater than 95% as determined by SEC-HPLC.

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