Mouse IL-5 R alpha/CD125 Protein (ILR-MM15R)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 0.495 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Asp18-His339
Catalog #ILR-MM15R
Regular price $210.00
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Product Description
Recombinant Mouse IL-5 R alpha/CD125 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp18-His339.
Product Background
Interleukin‑5 Receptor alpha (IL‑5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5.
Product Category
Recombinant Protein
Target
IL-5 R alpha
Synonyms
CD125; CDw125CD125; HSIL5R3; IL-5 R alpha; IL-5R subunit alpha; IL5R; IL5RA; IL-5Ra; MGC26560
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Asp18-His339
Molecular Weight
The protein has a predicted MW of 37.7 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Activity
The affinity constant of 0.495 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCl (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse IL-5 R alpha, His Tag immobilized on CM5 Chip can bind Mouse IL-5, His Tag with an affinity constant of 0.495 uM as determined in SPR assay (Biacore T200).
Mouse IL-5 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse IL-5 R alpha is greater than 95% as determined by SEC-HPLC.

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