Mouse IL-6 R alpha/CD126 Protein (ILR-MM16R)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Leu20-Pro364

Catalog: ILR-MM16R

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Product Description Recombinant Mouse IL-6 R alpha/CD126 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu20-Pro364.

Product Background

The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expressed.

Product Category

Recombinant Protein

Target

IL-6 R alpha/CD126

Gene/Protein ID

P22272

Species

Mouse

Exact Sequence

Leu20-Pro364
Molecular Weight The protein has a predicted MW of 39.21 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Mouse IL-6 R alpha is greater than 95% as determined by SEC-HPLC.
Mouse IL-6 R alpha on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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