Mouse IL-6 R alpha/CD126 Protein (ILR-MM16R)
Mouse IL-6 R alpha/CD126 Protein (ILR-MM16R)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Leu20-Pro364
Catalog #ILR-MM16R
Regular price $315.00
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Product Description

Recombinant Mouse IL-6 R alpha/CD126 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu20-Pro364.

Product Background

The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expressed.

Product Category

Recombinant Protein / Antibody discovery

Protein

IL-6 R alpha/CD126

Synonyms

IL-6R subunit alpha; IL-6R-alpha; IL-6RA; IL-6R 1; IL6R; CD126; IL6RQ; gp80

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Leu20-Pro364

Molecular Weight

The protein has a predicted MW of 39.21 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse IL-6 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse IL-6 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse IL-6 R alpha is greater than 95% as determined by SEC-HPLC. The purity of Mouse IL-6 R alpha is greater than 95% as determined by SEC-HPLC.

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