Mouse IL-6 R alpha/CD126 Protein (ILR-MM16R)
Catalog: ILR-MM16R
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| Product Description | Recombinant Mouse IL-6 R alpha/CD126 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Leu20-Pro364. |
Product Background |
The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expressed. |
Product Category |
Recombinant Protein |
Target |
IL-6 R alpha/CD126 |
| Accession | |
Species |
Mouse |
Amino Acid Range |
Leu20-Pro364 |
| Molecular Weight | The protein has a predicted MW of 39.21 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Mouse IL-6 R alpha is greater than 95% as determined by SEC-HPLC. |
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Mouse IL-6 R alpha on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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