Mouse IL-7 R alpha/CD127 Protein (IL7-MM2RA)
Mouse IL-7 R alpha/CD127 Protein (IL7-MM2RA)
Mouse IL-7 R alpha/CD127 Protein (IL7-MM2RA)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human IL-7, No Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-7 R alpha, hFc Tag with the EC50 of 10.4ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Glu21-Asp239
Catalog #IL7-MM2RA
Regular price $270.00
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Product Description

Recombinant Mouse IL-7 R alpha/CD127 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu21-Asp239.

Product Background

Interleukin 7 (IL-7) and its receptor (IL-7R, a heterodimer of IL-7Rα and γc) are essential for normal lymphoid development. IL-7 and IL-7R activate three main pathways: STAT5, PI3K/Akt/mTOR and MEK/Erk, ultimately leading to the promotion of leukemia cell viability, cell cycle progression and growth.

Product Category

Recombinant Protein / Antibody discovery

Protein

IL-7 R alpha/CD127

Synonyms

IL-7R alpha; IL7Ra; CD127; CDW127; IL7Rα

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Glu21-Asp239

Molecular Weight

The protein has a predicted MW of 51.74 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human IL-7, No Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-7 R alpha, hFc Tag with the EC50 of 10.4ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-hFc

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 24 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human IL-7, No Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-7 R alpha, hFc Tag with the EC50 of 10.4ng/ml determined by ELISA (QC Test). Immobilized Human IL-7, No Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Mouse IL-7 R alpha, hFc Tag with the EC50 of 10.4ng/ml determined by ELISA (QC Test).
Mouse IL-7 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse IL-7 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse IL-7 R alpha is greater than 95% as determined by SEC-HPLC. The purity of Mouse IL-7 R alpha is greater than 95% as determined by SEC-HPLC.

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