Name: Mouse Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer Protein, Ultra Low Endotoxin (ITG-MM1A1-UL)
Brand: KactusBio
SKU: ITG-MM1A1-UL-100UG
Price: 454.0 USD
Availability: InStock

Mouse Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer Protein, Ultra Low Endotoxin (ITG-MM1A1-UL)

Mouse ITGA1&ITGB1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Mouse ITGA1&ITGB1 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Phe29-Pro1141(ITGA1) acidic tail & Gln21-Asp728(ITGB1) basic tail

Catalog #ITG-MM1A1-UL

Size

100UG

500UG

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Product Description	Recombinant Mouse Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGA1.It contains Phe29-Pro1141(ITGA1) acidic tail and Gln21-Asp728(ITGB1) basic tail.
Product Background	Integrin α1β1 is a heterodimer of the Integrin subunits alpha 1 and beta 1 and is one of four collagen‑binding integrins, it preferentially binds Collagens I, IV, VI, XIII and XVI, but also binds Laminin. Integrin α1β1 is widely expressed in mesenchyme and the immune system, as well as a minority of epithelial tissues. It can suppresse EGFR signaling, increase expression of Caveolin-1, reduce production of reactive oxygen species, regulate collagen expression, regulate MMP collagenase and gelatinase activity, and mediates the renal basement membrane disorder Alport syndrome.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer
Synonyms	Integrin alpha 1 beta 1; alpha 1 beta 1; alpha 1; beta 1; ITGA1&ITGB1; ITGA&ITGB;Integrin alpha 1 β 1; alpha A1 β 1; β 1
Accession	Q3V3R4(ITGA1)&P09055-1(ITGB1)
Species	Mouse
Biotinylated	no
Amino Acid Range	Phe29-Pro1141(ITGA1) acidic tail & Gln21-Asp728(ITGB1) basic tail
Molecular Weight	The protein has a predicted MW of 129.00 kDa (ITGA1) & 82.80 kDa (ITGB1). Due to glycosylation, the protein migrates to 140-200 kDa (ITGA1) and 100-115 kDa (ITGB1) based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.01 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse ITGA1&ITGB1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse ITGA1&ITGB1 is greater than 95% as determined by SEC-HPLC.