Name: Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein (ITG-MM1LB)
Brand: KactusBio
SKU: ITG-MM1LB-100UG
Price: 375.0 USD
Availability: InStock

Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein (ITG-MM1LB)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail

Catalog #ITG-MM1LB

Size

100UG

500UG

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Product Description	Recombinant Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail.
Product Background	Integrin αLβ2 is one member of the integrin family and also called leukocyte function-associated antigen-1 (LFA-1). It is widely expressed on T lymphocytes and controls the function and, in particular, the migration of immune cells[1]. Active αLβ2 can bind ICAM1/CD54, ICAM2, ICAM3 and JAM1[2].
Product Category	Recombinant Protein

Target	Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer
Synonyms	αLβ2; ITGAL&ITGB2; ITGAL; ITGB2
Accession	P24063-1(ITGAL)&P11835(ITGB2)
Species	Mouse
Biotinylated	no
Amino Acid Range	Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail
Molecular Weight	The protein has a predicted MW of 123.30 kDa (ITGAL) and 79.60 kDa (ITGB2). Due to glycosylation, the protein migrates to 160-180 kDa (ITGAL) and 90-105 kDa (ITGB2) based on Bis-Tris PAGE result.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Mouse ITGAL&ITGB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse ITGAL&ITGB2 is greater than 95% as determined by SEC-HPLC.

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