Name: Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein (ITG-MM1LB)
Brand: KactusBio
SKU: ITG-MM1LB-100UG
Price: 412.5 USD
Availability: InStock

Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein (ITG-MM1LB)

Mouse ITGAL&ITGB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Mouse ITGAL&ITGB2 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail

Catalog #ITG-MM1LB

Size

100UG

500UG

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Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein (ITG-MM1LB) Summary

Product Description	Recombinant Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGAL.It contains Tyr24-His1087 (ITGAL) acidic tail and Gln24-Asn702 (ITGB2) basic tail.
Product Background	Integrin αLβ2 is one member of the integrin family and also called leukocyte function-associated antigen-1 (LFA-1). It is widely expressed on T lymphocytes and controls the function and, in particular, the migration of immune cells[1]. Active αLβ2 can bind ICAM1/CD54, ICAM2, ICAM3 and JAM1[2].
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein (ITG-MM1LB) Specifications/Details

Protein	Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer
Synonyms	αLβ2; ITGAL&ITGB2; ITGAL; ITGB2
Accession	P24063-1(ITGAL)&P11835(ITGB2)
Species	Mouse
Biotinylated	no
Amino Acid Range	Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail
Molecular Weight	The protein has a predicted MW of 123.30 kDa (ITGAL) and 79.60 kDa (ITGB2). Due to glycosylation, the protein migrates to 160-180 kDa (ITGAL) and 90-105 kDa (ITGB2) based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Mouse ITGAL&ITGB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse ITGAL&ITGB2 is greater than 95% as determined by SEC-HPLC.