Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein (ITG-MM1LB)
Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein (ITG-MM1LB)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail
Catalog #ITG-MM1LB
Regular price $375.00
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Product Description
Recombinant Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail.
Product Background
Integrin αLβ2 is one member of the integrin family and also called leukocyte function-associated antigen-1 (LFA-1). It is widely expressed on T lymphocytes and controls the function and, in particular, the migration of immune cells[1]. Active αLβ2 can bind ICAM­1/CD54, ICAM­2, ICAM3 and JAM­1[2].
Product Category
Recombinant Protein
Target
Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer
Synonyms
αLβ2; ITGAL&ITGB2; ITGAL; ITGB2
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail
Molecular Weight
The protein has a predicted MW of 123.30 kDa (ITGAL) and 79.60 kDa (ITGB2). Due to glycosylation, the protein migrates to 160-180 kDa (ITGAL) and 90-105 kDa (ITGB2) based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse ITGAL&ITGB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse ITGAL&ITGB2 is greater than 95% as determined by SEC-HPLC.

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