Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein (ITG-MM1LB)
Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein (ITG-MM1LB)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail
Catalog #ITG-MM1LB
Regular price $375.00
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Product Description

Recombinant Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail.

Product Background

Integrin αLβ2 is one member of the integrin family and also called leukocyte function-associated antigen-1 (LFA-1). It is widely expressed on T lymphocytes and controls the function and, in particular, the migration of immune cells[1]. Active αLβ2 can bind ICAM­1/CD54, ICAM­2, ICAM3 and JAM­1[2].

Product Category

Recombinant Protein / Antibody discovery

Protein

Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer

Synonyms

αLβ2; ITGAL&ITGB2; ITGAL; ITGB2

Accession

Species

Mouse

Biotinylated

no

Amino Acid Range

Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail

Molecular Weight

The protein has a predicted MW of 123.30 kDa (ITGAL) and 79.60 kDa (ITGB2). Due to glycosylation, the protein migrates to 160-180 kDa (ITGAL) and 90-105 kDa (ITGB2) based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse ITGAL&ITGB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse ITGAL&ITGB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse ITGAL&ITGB2 is greater than 95% as determined by SEC-HPLC. The purity of Mouse ITGAL&ITGB2 is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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