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Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein, Ultra Low Endotoxin (ITG-MM1LB-UL) Summary
Product Description |
Recombinant Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGAL.It contains Tyr24-His1087 (ITGAL) acidic tail and Gln24-Asn702 (ITGB2) basic tail. |
Product Background |
Integrin αLβ2 is one member of the integrin family and also called leukocyte function-associated antigen-1 (LFA-1). It is widely expressed on T lymphocytes and controls the function and, in particular, the migration of immune cells[1]. Active αLβ2 can bind ICAM1/CD54, ICAM2, ICAM3 and JAM1[2]. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer Protein, Ultra Low Endotoxin (ITG-MM1LB-UL) Specifications/Details
Protein |
Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer |
Synonyms |
αLβ2; ITGAL&ITGB2; ITGAL; ITGB2 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail |
Molecular Weight |
The protein has a predicted MW of 123.30 kDa (ITGAL) and 79.60 kDa (ITGB2). Due to glycosylation, the protein migrates to 160-180 kDa (ITGAL) and 90-105 kDa (ITGB2) based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.01 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
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Mouse ITGAL&ITGB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Mouse ITGAL&ITGB2 is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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