Product Description |
Recombinant Mouse ITK Protein is expressed from Baculovirus-Insect Cells(Sf9) with His tag and GST tag at the N-terminus and Strep-II tag at the C-terminus.It contains Arg347-Leu625. |
Product Background |
ITK (IL-2-inducible tyrosine kinase) belongs to the Tec family kinases and is mainly expressed in T cells. It is involved in TCR signalling events driving processes like T cell development as well as Th2, Th9 and Th17 responses thereby controlling the expression of pro-inflammatory cytokines. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Protein |
ITK |
Synonyms |
Kinase EMT; Kinase TLK; Emt; Tlk; Tsk; Tcsk |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Arg347-Leu625 |
Molecular Weight |
The protein has a predicted MW of 61.42 kDa same as Bis-Tris PAGE result. |
Product Tag |
N-His-GST, C-Strep-II |
Expression System |
Baculovirus-Insect Cells(Sf9) |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 50mM Tris, 100mM NaCl, 10% Glycerol, 0.5mM GSH (pH 7.5). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Mouse ITK on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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