|Recombinant Mouse ITK Protein is expressed from Baculovirus-Insect Cells with His tag and GST tag at the N-terminus and Strep-II tag at the C-terminus.It contains Arg347-Leu625.
|ITK (IL-2-inducible tyrosine kinase) belongs to the Tec family kinases and is mainly expressed in T cells. It is involved in TCR signalling events driving processes like T cell development as well as Th2, Th9 and Th17 responses thereby controlling the expression of pro-inflammatory cytokines.
|The protein has a predicted MW of 61.42 kDa same as Tris-Bis PAGE result.
|> 95% as determined by Tris-Bis PAGE
|Less than 1EU per ug by the LAL method.
|Shipped with dry ice.
|Supplied as 0.22 um filtered solution in 50mM Tris, 100mM NaCl, 10% Glycerol, 0.5mM GSH (pH 7.5).
|Stability And Storage
|Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.